Season
- Season 21 2013-01-02
- Season 20 2012-01-03
- Season 19 2011-01-03
- Season 18 2010-03-01
- Season 17 2008-06-02
- Season 16 2007-09-17
- Season 15 2006-09-18
- Season 14 2005-06-06
- Season 13 2004-06-07
- Season 12 2003-06-02
- Season 11 2002-06-03
- Season 10 2002-04-30
- Season 9 2000-08-01
- Season 8 1999-07-30
- Season 7 1998-02-26
- Season 6 1997-12-05
- Season 5 1996-09-16
- Season 4 1996-03-07
- Season 3 1994-11-28
- Season 2 1993-06-25
- Season 1 1992-05-25
- Season 0 2014-02-06
Episode
- Episode 1: William Shatner; Chelsea Handler; Newton Faulkner
- Episode 2: Liv Tyler; Judd Apatow; Usher
- Episode 3: Jeff Foxworthy; Arianna Huffington; N.E.R.D.
- Episode 4: Dustin Hoffman; Gordon Ramsay; Flobots
- Episode 5: Will Smith; Pete Sampras; Ed Harcourt
- Episode 6: Russell Brand; Bill Engvall; Aimee Mann
- Episode 7: Justin Timberlake; Karen Allen; Sheryl Crow
- Episode 8: Dana Carvey; Spencer Breslin; Priscilla Ahn
- Episode 9: Mike Myers; Abigail Breslin; David Cook
- Episode 10: Larry the Cable Guy; Bob Costas; Ashanti
- Episode 11: Anne Hathaway; Gabriel Iglesias; Amos Lee
- Episode 12: Don Rickles; Charles Barkley, Kenny Smith, Ernie Johnson; Jewel
- Episode 13: The Rock; Tom Papa; Against Me!
- Episode 14: Wanda Sykes; James McAvoy; Duffy
- Episode 15: Bette Midler; Al Roker; Bette Midler
- Episode 16: Selma Blair; Kevin Nealon; Steve Tyrell
- Episode 17: Aaron Eckhart; Los Lonely Boys; Dara Torres
- Episode 18: Sara Bareilles; Jarod Miller
- Episode 19: Adam Carolla; Kathy Griffin; Wynton Marsalis; Willie Nelson
- Episode 20: Elizabeth Banks; Michael Caine
- Episode 21: Will Ferrell; Mary McCormack; James Hunter
- Episode 22: David Duchovny; Reese Hoffa; Jakob Dylan
- Episode 23: John C. Reilly; Venus Williams; Gavin Rossdale
- Episode 24: David Spade; Jordana Spiro; Coldplay
- Episode 25: Tim Allen; Demi Lovato; One Republic
- Episode 26: Kyra Sedgewick; Chris Matthews; Alanis Morissette
- Episode 27: Gillian Anderson; Dave Attell; The Duke Spirit
- Episode 28: Kevin Costner; D.L. Hughley; The Time
- Episode 29: Kelsey Grammer; Hugh Rowland; Drew Sherwood; Gavin Degraw
- Episode 30: Kevin Spacey; Triumph the Insult Comic Dog; Jesse McCarthy
- Episode 31: Julie Scardina; Brendan Fraser; Gnarls Barkley
- Episode 32: Seth Rogen; Joan Allen; Third Day
- Episode 33: Rainn Wilson; Emeril Lagasse; Sergio Mendes Ft. Ledisi
- Episode 34: Rosie Perez; Robin Thicke
- Episode 35: Bill Cosby; Emma Stone
- Episode 36: Ben Stiller; the Jonas Brothers
- Episode 37: Robert Downey Jr.; Anna Faris; Toby Keith
- Episode 38: Jack Black; Conor Oberst
- Episode 39: Nick Nolte; Solomon Burke
- Episode 40: Scarlett Johansson; Luke Ford; Chris Cornell
- Episode 41: John McCain; Dara Torres; Juliana Hatfield
- Episode 42: Norm MacDonald; Gordon Ramsay; B.B. King
- Episode 43: Bill Maher; Low vs Diamond
- Episode 46: Josh Brolin, Chelsea Handler, The Killers
- Episode 47: Heidi Klum, Robert Pattinson, Seal
- Episode 48: Debra Messing, Cody Willard, Celine Dion
- Episode 49: Kathy Griffin, David Frost, Colbie Caillat
- Episode 50: Michael Phelps, JB Smoove
- Episode 51: Brian Williams, Kirk Fox, Common
- Episode 52: Cate Blanchett, Tim Reid & Tom Dreesen, Taylor Swift
- Episode 53: Will Smith, Paula Deen, k.d. lang
- Episode 55: Kate Beckinsale, Sean "Diddy" Combs, Sara Bareilles & Ingrid Michaelson
- Episode 56: Wanda Sykes, Michael Phelps, Lyle Lovett
- Episode 57: Jamie Foxx, David Gregory
- Episode 58: Kate Winslet, Dame Edna, Sheryl Crow
- Episode 59: Jim Carrey, Rosario Dawson, Relient K
- Episode 60: Charlize Theron; Matt Lucas & David Walliams
- Episode 61: Adam Sandler, Zooey Deschanel, Los Lonely Boys
- Episode 62: James Franco, Doris Kearns Goodwin, Melissa Etheridge
- Episode 64: Owen Wilson, Julie Scardina, Natalie Cole
- Episode 65: Terry Bradshaw, Jack Witherspoon, Iron & Wine
- Episode 66: Queen Latifah, Adam Carolla, Pussycat Dolls
- Episode 67: Anne Hathaway, Brady Barr, Jeff Dunham
- Episode 68: Dustin Hoffman, Mary Lynn Rajskub, Lady GaGa
- Episode 69: Daniel Craig, Taraji P. Henson, Eagles of Death Metal
- Episode 70: David Duchovny, Richard Roeper, The All-American Rejects
- Episode 71: Mickey Rourke, Toni Collette, John Legend
- Episode 72: Cherie Blair, Ralph Fiennes, Brett Dennen
- Episode 73: Kevin James, Emma Roberts, MuteMath
- Episode 74: Hugh Laurie, Chuck Todd, Band From TV
- Episode 75: Jimmy Fallon, Neil DeGrasse Tyson, Lee Ann Womack
- Episode 76: Wanda Sykes, Bernice Gallego, Buckcherry
- Episode 77: Howie Mandel, Jerome Bettis, Lady Antebellum
- Episode 79: Marisa Tomei, Dr. Grey Stafford, Ty Barnett
- Episode 80: Michelle Obama; Chris Rock; Darius Rucker
- Episode 81: Rainn Wilson, Nikki Glaser, Hoobastank
- Episode 82: Dakota Fanning, Bradley Cooper, the Neville Brothers
- Episode 83: Jenna Fischer, Justin Long, Franz Ferdinand
- Episode 84: Elizabeth Banks, Dev Patel, James Morrison
- Episode 85: Kate Winslet, Danny Boyle, Akon
- Episode 86: Penelope Cruz, D.L. Hughley, Sara Bareilles
- Episode 87: Drew Barrymore, Serena Williams, will.i.am
- Episode 88: Jennifer Aniston, Santonio Holmes, Jamey Johnson
- Episode 89: Dave Salmoni, Frank Langella, Ben Lee
- Episode 90: Simon Baker, Heidi Montag and Spencer Pratt, Duffy
- Episode 91: Bill Maher, Viola Davis, Raphael Saadiz
- Episode 92: Anderson Cooper; Steve Byrne; Sarah McLachlan
- Episode 93: Miley Cyrus; Jason Statham; David Cook
- Episode 94: Kiefer Sutherland; Lisa Lampanelli; Barry Manilow
- Episode 95: Larry the Cable Guy, Chris Matthews, Adele
- Episode 96: Bill Maher, Kristin Chenoweth, Nickelback
- Episode 97: Hugh Jackman, Tenacious D
- Episode 98: Jay Mohr, Marjorie Johnson, Scott Weiland
- Episode 99: Ron Howard, Jonas Brothers
- Episode 100: Larry the Cable Guy, Malin Akerman, the Fray
- Episode 101: Bob Newhart, Rachel Maddow, Bettye Lavette
- Episode 102: Russell Brand, Neko Case
- Episode 103: Jarrod Miller, Sienna Miller, Tom Jones
- Episode 104: Christina Ricci, Papa Roach
- Episode 105: Elisabeth Hasselbeck, Demetri Martin, Rocco De Luca & The Burden
- Episode 106: Whoopi Goldberg, Elle Fanning, Keyshia Cole
- Episode 107: Ellen DeGeneres, Christopher Mintz, Raul Malo
- Episode 108: Dwayne Johnson, Heather Headley
- Episode 109: John Krasinski, Kara DioGuardi, Randy Travis
- Episode 110: Tom Cruise, Frank Caliendo, The Cure
- Episode 111: Portia de Rossi, D.L. Hughley, Soundtrack of Our Lives
- Episode 112: Reese Witherspoon, Keith Olbermann, Naturally 7
- Episode 113: President Barack Obama, Garth Brooks
- Episode 117: Robin Williams, Freida Pinto, Johnny Mathis
- Episode 151: Charlie Sheen, Arianna Huffington, Lisa Hannigan
- Episode 168: Seth Rogen, Guy Fieri, Chris Cornell
- Episode 169: Simon Cowell, Randy Jackson, Ryan Seacrest, John Cena, Playing For Change
- Episode 170: Condoleezza Rice, Bill Hader, PJ Harvey & John Parish
- Episode 171: Halle Berry, Frank Caliendo, Prince
- Episode 172: Paul Giamatti, Emma Roberts, Prince
- Episode 173: Dana Carvey, Billy Mays, Prince
- Episode 174: Vin Diesel, Lisa Lampanelli, Gavin DeGraw
- Episode 175: Amy Poehler, Paul Walker, Fall Out Boy
- Episode 176: Michael Caine, Dennis Rodman, Christopher Guest, Michael McKean, Harry Shearer
- Episode 177: Ben Affleck, Taylor Swift
- Episode 178: Miley Cyrus, Tom Lennon
- Episode 179: Sen. John McCain, Kristin Chenoweth, Billy Ray Cyrus
- Episode 180: Jamie Foxx, Carol Leifer, the Airborne Toxic Event
- Episode 181: Don Rickles, Richard Engel, Chris Botti featuring John Mayer
- Episode 182: Jessica Alba, Bob Saget, Jonny Lang
- Episode 183: Charles Barkley, Leslie Mann, TV on the Radio
- Episode 184: Martha Stewart, Tracey Ullman, the Killers
- Episode 185: Hugh Jackman, Abigail Breslin, Ida Maria
- Episode 186: Robert Downey Jr., Alexandra Wentworth, George Wallace
- Episode 187: Eric Bana, Marjorie Johnson, Big Bad Voodoo Daddy
- Episode 188: Michael Douglas, Chelsea Handler, Country Bones
- Episode 189: Jimmy Fallon, Chris Matthews, Zac Brown Band
- Episode 190: Matthew McConaughey, Earvin "Magic" Johnson, Starsailor
- Episode 191: Arsenio Hall, Jules Sylvester, Ziggy Marley
- Episode 192: Anderson Cooper, Kathleen Madigan, Eli Young Band
- Episode 193: Howie Mandel, Alec Greven, Robert Randolph & the Clark Sisters
- Episode 194: Tim Allen, John Cho, Van Morrison
- Episode 195: Adam Sandler, Judd Apatow, Soulja Boy Tellem
- Episode 196: Jamie Lee Curtis, Jonah Hill, Jewel
- Episode 197: Russell Brand, Elizabeth Banks, Ciara
- Episode 198: Dennis Miller, Calvin Borel, Kelly Clarkson
- Episode 199: Kevin Spacey, Roberta McCain, Yusuf
- Episode 200: Katie Couric, Ewan McGregor, the Decemberists
- Episode 201: Kevin Bacon, Julie Scardina, Kings of Leon
- Episode 202: Cameron Diaz, Kirk Fox, Blink 182
- Episode 203: Terry Bradshaw, 8-year-old piano prodigy Ethan Bortnick, Blink 182
- Episode 204: Bill Maher, Adam Richman, Mandy Moore
- Episode 205: Andy Samberg, "American Idol" winner Kris Allen, Lionel Richie
- Episode 206: Brian Williams, Jesse James, Tori Amos
- Episode 207: Mel Gibson, Lyle Lovett
- Episode 208: Gov. Arnold Schwarzenegger, Dwight Yoakam
- Episode 209: Wanda Sykes, Sarah McLachlan
- Episode 210: Billy Crystal, Prince
- Episode 211: Conan O'Brien, James Taylor
- Episode 212: 17 Dec. 2008
The Tonight Show with Jay Leno Season 17 Simon Cowell, Randy Jackson, Ryan Seacrest, John Cena, Playing For Change
Jay Leno hosts some of the biggest celebrities in the world.
